The Efficacy and Safety of Traditional Chinese Medicine Tonifying-Shen (Kidney) Principle for Primary Osteoporosis

Autor: Junquan Liang et al

Journal: Evidence-Based Complementary and Alternative Medicine Volume 2020, Article ID 5687421, englisch

Objective. This study aimed to appraise the efficacy and safety of the tonifying-Shen (kidney) principle (TS (TK) principle) for primary osteoporosis (POP).

Methods. Randomized controlled clinical trials (RCTs) using the TS (TK) principle for POP were searched from eight electronic databases to search for relevant literature that was published from the initiation to September 2019. Two reviewers performed study selection, data extraction, data synthesis, and quality assessment independently. Review Manager 5.3 software was used to assess the risk of bias and conduct the data synthesis. We assessed the quality of evidence for outcomes by using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system.

Results. Thirty-six studies with 3617 participants were included. Meta-analysis showed a consistently superior effect of the TS (TK) principle combined with conventional Western medicine (CWM) in terms of total effectiveness rates (RR = 1.28; 95% CI (1.23, 1.33); ), BMD of the lumbar spine (SMD = 0.71; 95% CI (0.47, 0.95); ) and proximal femur (SMD = 0.94; 95% CI (0.49, 1.38); ), TCM symptom integral (SMD = −1.23; 95% CI (−1.43, −1.02); ), and VAS scores (SMD = −3.88; 95% CI (−5.29, −2.46); ), when compared to using CWM alone and with significant differences. Besides, in respect of adverse effects, it showed no significant statistical difference between the experimental and control groups, RR = 0.99 and 95% CI (0.65, 1.51), .

Conclusion. Our meta-analysis provides promising evidence to suggest that using the TS (TK) principle combined with CWM for POP is more effective than using CWM alone. Also, both of them are safe and reliable for POP.

Andere Benutzer haben sich neben diesem auch noch folgende Artikel angesehen:

Treatment of 242 Cases of Neck Sprain by Electric Stimulation of Acupoints
Sun Faxuan, Tang Qiaoyun; Zhu Jiguang; 1988

Treatment of Hepatic Abscesses Supplemented by TCM - A Comparative Observation of Therapeutic Effects on 64 Patients
Zeng Qinghua; 1988

Acupuncture Treatment of Raynaud's Disease - A Report of 43 Cases
Bao Jiazhu; 1988


Vorheriger Artikel


Nächster Artikel

Link zum Journal